Who was the first player to score 5 goals in a Premier League game?

Manchester United’s Andrew Cole became the first player to score five goals in a Premier League game in a 9-0 win over Ipswich Town on 4 March 1995.

The only other players to have scored five goals in a Premier League game are as follows:

Jermain Defoe: Tottenham Hotspur 9-1 Wigan Athletic on 22 November 2009
Dimitar Berbatov: Manchester United 7-1 Blackburn Rovers on 27 November 2010
Sergio Aguero: Manchester City 6-1 Newcastle United on 3 October 2015